1893 Tsumura is founded in central Tokyo to produce and sell Chujo-to, herbal treatment for women's disorders. 1924 Tsumura Research Institute for Pharmaceutical Science and Tsumura Herbal Garden open. Publication of The Journal of Japanese Botany commence. 1954 Introduction of Chujo-to L'Amour, tablet-form herbal product for women. 1964 Shizuoka Plant begins operation. 1965 OTC Kampo drug sales begin. 1976 For the first time, Kampo medicines (33 prescriptions) are listed on the National Health Insurance Drug Price Tariff and approved for reimbursement. 1980 Tsumura becomes publicly held company, with its stock listed on the second section of the Tokyo Stock Exchange. Tsumura Research Institute for Pharmacology is established. 1982 Tsumura's stock listing is upgraded to the first section of the Tokyo Stock Exchange. 1983 Ibaraki plant starts operation. 1987 Number of Kampo medicines included in the National Health Insurance Drug Price Tariff reaches 129. 1993 Tsumura holds International Kampo Symposium to mark 100th anniversary of its establishment. 1994 Tsumura introduces Metalite and Astat as new chemical entities. 1995 Hachizaemon Kazama becomes president. 1996 Contract concluded with Phytera, Inc. of the United States for joint research on new compounds derived from medicinal plants. 2001 Plants of Ibaraki and Shizuoka obtained ISO 14001. 2004 Junichi Yoshii becomes president. 2006 Sell the head office and Rokubancho buildings in March 2006. Spin off the household products business.