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October 9, 2008
About the transfer of approval to production and marketing of ASTAT®,
an external-use, anti-fungal drug for ethical use

Tsumura & Co. (Headquarters: Tokyo, President: Junichi Yoshii) today announces a trilateral agreement on the transfer of approval to the production and marketing of ASTAT® (generic name: Lanoconazole), an external-use anti-fungal drug for ethical use, to Maruho Co., Ltd. (Head office: Osaka, President: Koichi Takagi. Hereinafter "Maruho"). ASTAT® is jointly developed by Tsumura and Nihon Nohyaku Co., Ltd. (Head office: Tokyo, President: Shukichi Ohuchi. Hereinafter "Nihon Nohyaku") and is made and marketed by Tsumura.

Since September 1994, Tsumura has marketed ASTAT® by receiving drug substances from Nihon Nohyaku. Available in three forms including ASTAT® Cream, ASTAT® Solution and ASTAT® Ointment, ASTAT® is extensively used in the treatment of many patients.
At present, Tsumura markets ASTAT® Cream, ASTAT® Solution and ASTAT® Ointment. The above agreement will allow Maruho, from next spring, to market all of the three forms of ASTAT®, send related information to medical institutions and gather that information.



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