※Please note that the actual color of the product may appear slightly different depending on your device setting.
※The above crude drug photos are for illustrative purposes only.

Tsumura-Kampo Daiokanzoto Extract Granules

Category 2 OTC medicines



Constipation and its accessory symptoms such as heavy head, hot flashes, eczema/dermatitis, pimple (acne), loss of appetite (anorexia), abdominal bloating, abnormal intestinal fermentation, and hemorrhoid.


2 packets (3.75 g) of this medicine contain 0.75 g of Daiokanzoto extract of the following mixed crude drugs;

JP Rhubarb 2.0 g
JP Glycyrrhiza 1.0 g

(JP: The Japanese Pharmacopoeia)
Inactive ingredients: JP Magnesium Stearate、JP Lactose Hydrate.


Take the following dosages with water or warm water before a meal.

Age One dosage Daily dosage
15 years and over 1 packet (1.875 g) 2 times a day
7-14 years 2/3 packet
4-6 years 1/2 packet
2-3 years 1/3 packet
Less than 2 years Do not use

[Cautions] This medication should be given to children only under adult supervision



  1. Store in a cool, dry place free from direct sunlight.

  2. Keep all medication out of the reach of children.

  3. When you take this medicine in divided dose, fold over the opened edge of the packet and store it. The remaining medicine should be taken within 2 days.

  4. Since the medicine contains crude drugs, the granules color may vary for individual products,however this has no influence on the efficacy of this medicine.

  5. Do not take this medicine after the expiration date.


To be avoided

Failure to observe the following may result in the symptoms worsening or the occurrence of adverse reactions/accidents.

  1. This medication should not be used in combination with the following medications: Other cathartic agents.

  2. Women who are nursing should not take this medicine. If those women take it, avoid breast feeding.

Who should seek consultation

  1. The following persons should consult a physician, pharmacist, or registered distributor before taking this medicine.

    1. Persons undergoing medical treatment from a physician.
    2. Pregnant women or women suspected of being pregnant.
    3. Persons who is physically weak (declining of strength or constitutional weakness).
    4. Persons with weak stomach and intestine who have a tendency to diarrhea.
    5. Elderly persons.
    6. Persons with the following symptoms: edema.
    7. Persons diagnosed as having the following: hypertension, heart disease, kidney disease.
  2. The following symptoms may be adverse reactions to this medication. If any of these symptoms occur, stop taking this medicine mmediately and consult a physician, pharmacist, or registered distributor. Take the instruction leaflet with you.

    Related areas Symptoms
    Gastrointestinal system

    Diarrhea with severe abdominal pain, abdominal pain

    In very rare cases the following serious symptoms may occur. In this case, consult a physician immediately.

    Symptoms' name Symptoms
    Pseudoaldosteronism, myopathy

    In addition to listlessness, stretched feeling, and stiffness of hands and feet, feeling of weakness and muscular pain will appear and gradually worsen.

  3. A following symptom may appear after taking this medicine. If the symptom continues or worsen, consult a physician, pharmacist or registered distributor. Take this leaflet with you: diarrhea

  4. Stop taking this medicine and consult a physician, pharmacist or registered distributor if symptoms do not improve after taking this medicine for 5 to 6 days. Take this leaflet with you.

  5. If you take this medicine regularly for a long periods, consult a physician, pharmacist or registered distributor.

Production of this product has been approved for domestic sales in accordance with the Pharmaceutical Affairs Law of Japan.